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KMID : 0358419630060090381
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Korean Journal of Obstetrics and Gynecology
1963 Volume.6 No. 9 p.381 ~ p.385
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Electrophoretic Fractionation of Proteins in Maternal and Fetal Serum and Amniotic Fluid
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신면우/Shin MW
박성기/백운송/박성관/Park SK/Paik US/Park SK
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Abstract
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1) Amniotic fluid from fourteen cases of pregnant women was fractionated for proteins by paper elctrophoresis and the resulting patterns were compared with those of maternal and fetal serum proteins. 2) A/G ratio was highest in amniotic fluid. Alpha-2 and gamma globulin concentration in amniotic fluid was significantly lower than in maternal serum protein, suggesting the possiple role of iotic fluid was significantly lower than in maternal serum protein, suggesting the possiple role of serum molecular weight in traversing fetal membrane. 3) The relative concentration of amniotic fluid proteins was similar to maternal serum protein pattern. Furthermore, the patterns showed a closer similarity to those of the dilysate of maternal through fetal membrane against normal saline solution. 4) No Particularly remarkable changes in amniotic fluid protein patterns were observed in two respective cases og hydramnios and mild pre-eclampsia. 5) Trans-addominal amniocentesis in eight cases proved to be a satisfactory method of obtaining good samples of amniotic fluid with little danger. 6) Brief review of literatures was made in regard to the origin of amnioitic fluid protein and its nutritional value to the fetus.
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